Switching of bacterial adhesion to a glycosylated surface by reversible reorientation of the carbohydrate ligand.

摘要: The surface recognition in many biological systems is guided by the interaction of carbohydrate-specific proteins (lectins) with carbohydrate epitopes (ligands) located within unordered glycoconjugate layer (glycocalyx) cells. Thus, for recognition, respective ligand has to reorient a successful matching event. Herein, we present first time model system, which only orientation altered controlled manner without changing quality itself. key this orientational control embedding into an interfacial system and use photoswitchable mechanical joint, such as azobenzene.