Assessment of hypothalamic-pituitary function in women after external head irradiation.
作者： KO-EN HUANG
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摘要: To account for hypopituitarism in patients who received 60Co head irradiation nasopharyngeal neoplasia, hypothalamic-pituitary function was evaluated 12 women, aged 19–40 yr, 1–13 yr after the irradiation. The hypothalamicpituitary area a dose of about 6000–6500 rads. Serum basal LH and FSH levels as well their responses to 25 µg iv LRH were measured by RIA results compared with early follicular phase 5 normal cycling women. In 8 patients, serum LH, FSH, PRL also before during fourth day clomiphene administration (100 mg/day days). Among irradiated 3 had oligomenorrhea, amenorrhea, galactorrhea. mean (5.80 ± 0.68 mlU/ml) (6.23 0.79 LRH-stimulated peak (31.33 4.26 (14.84 1.80 significantly (P < 0.01) lower than those controls. magnitude individual gonadotropin respo...
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