Potassium Channels, Cell Cycle, and Tumorigenesis in the Central Nervous System

摘要: In addition to the well-understood role in action potential repolarization and control of brain homeostasis, potassium channels also play a fundamental controlling cellular proliferation. Here we wish summarize evidence supporting channels’ involvement tumorigenesis. We will first introduce basic concepts cell cycle central nervous system, then describe multiple roles their modulators system. Finally, focus on how tumors are controlled by channel regulation, linking tumorigenesis process re-entry. novel possible modulator channels, thus