The synthesis of messenger RNA without protein synthesis

作者: J.L. Stern , M. Sekiguchi , H.D. Barnner , S.S. Cohen

DOI: 10.1016/S0022-2836(64)80113-3

关键词:

摘要: Escherichia coli , deficient in the ability to synthesize thymine, uracil and an amino acid, a small fraction of their normal RNA from absence thymine acid. The synthesis even this is inhibited by concomitant DNA synthesis. Most (75%) made appears on ribosomes can be degraded these structures presence inorganic phosphate. When synthesized inducer β -galactosidase, permit rapid amount enzyme apparent inducer. These observations are consistent with hypothesis that essential acid protein largely messenger RNA.

参考文章(47)
Alexandra E. Shedlovsky, Boris Magasanik, A defect in histidine biosynthesis causing an adenine deficiency. Journal of Biological Chemistry. ,vol. 237, pp. 3725- 3730 ,(1962) , 10.1016/S0021-9258(19)84515-5
Denise Luzzati, Robert Guthrie, Studies of a purine- or histidine-requiring mutant of Escherichia coli. Journal of Biological Chemistry. ,vol. 216, pp. 1- 8 ,(1955) , 10.1016/S0021-9258(19)52278-5
Jesse C. Rabinowitz, W.E. Pricer, AN ENZYMATIC METHOD FOR THE DETERMINATION OF FORMIC ACID Journal of Biological Chemistry. ,vol. 229, pp. 321- 328 ,(1957) , 10.1016/S0021-9258(18)70618-2
Janet Lichtenstein, Seymour S. Cohen, Joel G. Flaks, Virus-induced acquisition of metabolic function. II. Studies on the origin of the deoxycytidylate hydroxymethylase of bacteriophage-infected E. coli. Journal of Biological Chemistry. ,vol. 234, pp. 1507- 1511 ,(1959)
Arthur Brown, A STUDY OF LYSIS IN BACTERIOPHAGE-INFECTED ESCHERICHIA COLI Journal of Bacteriology. ,vol. 71, pp. 482- 490 ,(1956) , 10.1128/JB.71.4.482-490.1956
Martin Lubin, Enrichment of auxotrophic mutant populations by recycling. Journal of Bacteriology. ,vol. 83, pp. 696- 697 ,(1962) , 10.1128/JB.83.3.696-697.1962
Hazel D. Barner, Seymour S. Cohen, THE ISOLATION AND PROPERTIES OF AMINO ACID REQUIRING MUTANTS OF A THYMINELESS BACTERIUM1 Journal of Bacteriology. ,vol. 74, pp. 350- 355 ,(1957) , 10.1128/JB.74.3.350-355.1957
Douglas A. MacFadyen, ESTIMATION OF FORMALDEHYDE IN BIOLOGICAL MIXTURES Journal of Biological Chemistry. ,vol. 158, pp. 107- 133 ,(1945) , 10.1016/S0021-9258(17)41599-7