Acute syphilitic posterior placoid chorioretinopathy: An infectious or autoimmune disease?

摘要: Abstract Purpose To report a case of acute syphilitic posterior placoid chorioretinopathy (ASPPC) that demonstrated partial resolution with immunosuppressive therapy secondary to misdiagnosis as Behcet's disease followed by relapse which was successfully treated the appropriate treatment. Observations A 34-year-old female patient presented our service complaints decreased vision in left eye (OS). She initially developed similar symptoms seven months prior presentation and diagnosed based on clinical picture papillitis, vasculitis chorioretinitis pole OS. started daily oral prednisone 60 mg weekly methotrexate 10mg her rheumatologist. The patient's ocular improved one month lesion but persistence papillitis. At time, dose 30 resulted chorioretinal lesions worsened visual acuity at time us. Extensive laboratory workup positive serology for syphilis. diagnosis made intravenous penicillin G 2 weeks. vitritis, resolved along improvement following Conclusions importance Ocular findings syphilis are heterogeneous may mimic variety diseases. ASPPC is rare manifestation its natural course underlying pathophysiology not well understood. However, irrespective mechanism disease, all patients should receive treatment prevent recurrence long-term functional damage.