Update and critical appraisal of combined timolol and carbonic anhydrase inhibitors and the effect on ocular blood flow in glaucoma patients

摘要: Topical hypotensive therapy with both timolol and carbonic anhydrase inhibitors has been shown to be efficacious at reducing intraocular pressure. Many prospective studies have also suggested that augment ocular blood flow vascular regulation independent of their effects. Although consistent in findings, these must cautiously interpreted due the limitations study design specific imaging modalities. The purpose this review is appraise critically evaluate current body literature investigating effects combined treatment topical patients glaucoma respect flow, visual function, optic nerve head structure.