Communication of radiation-induced signals in vivo between DNA repair deficient and proficient medaka (Oryzias latipes).

摘要: Radiation-induced bystander effects are established consequences of exposure to ionizing radiation. The operation this mechanism has been seen in vitro and also between fish, mammals, plants vivo where stress signals from treated organisms induce responses neighbors. In research shows that DNA repair deficient cells produce more toxic responses. To test two strains Japanese medaka were tested. One is a mutant, strain (ric2) the other, wildtype proficient (CAB). Irradiated fish swam with unirradiated partners mix match protocol. data suggest signals, when exposed radiation, same swimming them an altered response bystanders sham irradiated fish. More apoptosis was When mixed, either respond like donor strain. Measure...