Biological and clinical implications of EGFR mutations in lung cancer.

作者: Tetsuya Mitsudomi , Takayuki Kosaka , Yasushi Yatabe

DOI: 10.1007/S10147-006-0583-4

关键词:

摘要: … literatures on EGFR mutations and EGFR-TKIs. We … EGFR mutations in relation to EGFR-TKIs, the controversy about whether EGFR mutations account for all the clinical activity of EGFR-…

参考文章(73)
Long-Yun Li, Xiao-Tong Zhang, Shu-Lan Wang, Meng-Zhao Wang, Xin-Lin Mu, Wei Song, Improvements in quality of life and disease-related symptoms in patients with advanced non-small cell lung cancer treated with gefitinib. Chinese Medical Journal. ,vol. 118, pp. 1661- 1664 ,(2005)
Tetsuya Mitsudomi, Tetsuya Mitsudomi, Akira Ogami, Kosei Yasumoto, Toshihiro Osaki, Tsunehiro Oyama, Keizo Sugimachi, Kinue Nishida, Adi F. Gazdar, Kenji Sugio, Kenji Sugio, Loss of heterozygosity at 3p in non-small cell lung cancer and its prognostic implication. Clinical Cancer Research. ,vol. 2, pp. 1185- 1189 ,(1996)
Adi F. Gazdar, Shinichi Toyooka, Kazunori Tsukuda, Mitsune Tanimoto, Masahiro Tabata, Kouichi Ichimura, Masaaki Yano, Toshihide Tsuda, Hisayuki Shigematsu, Hiroshi Date, Kunitoshi Tomii, Nobuyoshi Shimizu, Hiroshi Ueoka, Motoi Aoe, Masaki Tokumo, Katsuyuki Kiura, The Relationship between Epidermal Growth Factor Receptor Mutations and Clinicopathologic Features in Non–Small Cell Lung Cancers Clinical Cancer Research. ,vol. 11, pp. 1167- 1173 ,(2005)
Tetsuo Kuroishi, Motokazu Suyama, Ryuzo Ueda, Hiroko Suzuki, Toshitada Takahashi, Yutaka Ariyoshi, Takashi Takahashi, p53 Mutations in Non-Small Cell Lung Cancer in Japan: Association between Mutations and Smoking Cancer Research. ,vol. 52, pp. 734- 736 ,(1992)
Takeshi Suzuki, Taku Nakagawa, Hideki Endo, Tetsuya Mitsudomi, Akira Masuda, Yasushi Yatabe, Takahiko Sugiura, Takashi Takahashi, Toyoaki Hida, The sensitivity of lung cancer cell lines to the EGFR-selective tyrosine kinase inhibitor ZD1839 ('Iressa'1) is not related to the expression of EGFR or HER-2 or to K-ras gene status Lung Cancer. ,vol. 42, pp. 35- 41 ,(2003) , 10.1016/S0169-5002(03)00278-2
Steven A. Ahrendt, P. Anthony Decker, Enas A. Alawi, Yong-ran Zhu, Montserrat Sanchez-Cespedes, Stephen C. Yang, George B. Haasler, André Kajdacsy-Balla, Michael J. Demeure, David Sidransky, Cigarette smoking is strongly associated with mutation of the K-ras gene in patients with primary adenocarcinoma of the lung. Cancer. ,vol. 92, pp. 1525- 1530 ,(2001) , 10.1002/1097-0142(20010915)92:6<1525::AID-CNCR1478>3.0.CO;2-H
Ming-Sound Tsao, Akira Sakurada, Jean-Claude Cutz, Chang-Qi Zhu, Suzanne Kamel-Reid, Jeremy Squire, Ian Lorimer, Tong Zhang, Ni Liu, Manijeh Daneshmand, Paula Marrano, Gilda da Cunha Santos, Alain Lagarde, Frank Richardson, Lesley Seymour, Marlo Whitehead, Keyue Ding, Joseph Pater, Frances A. Shepherd, Erlotinib in lung cancer - molecular and clinical predictors of outcome. The New England Journal of Medicine. ,vol. 353, pp. 133- 144 ,(2005) , 10.1056/NEJMOA050736
Nathan L. Kobrinsky, Marilyn G. Klug, Peggy Jo Hokanson, Diane E. Sjolander, Larry Burd, Impact of smoking on cancer stage at diagnosis. Journal of Clinical Oncology. ,vol. 21, pp. 907- 913 ,(2003) , 10.1200/JCO.2003.05.110