Immunoglobulin G antibody against Helicobacter pylori: clinical implications of levels found in serum.

摘要: The clinical significance of high levels antibody against Helicobacter pylori is still unclear. We sought to evaluate whether the serum could predict presence macroscopic gastroduodenal disease, identify factors that correlate with in a multivariate context, and determine predictive value for diagnosing H. infection. grades gastritis density colonization were scored separately using updated Sydney system antral body mucosa. An enzyme-linked immunosorbent assay (ELISA) quantitative detection IgG antibodies was performed. Of 170 dyspeptic patients, 105 (62%) had There no difference among endoscopic findings normal mucosa, chronic gastritis, duodenal ulcer. On linear regression analysis, status infection, mononuclear cell infiltration age correlated levels. negative 70 U/ml 98%. conclude do not severity diseases or pylori-infected patients. Higher are associated score corpus, older age. Setting gray zone necessary ELISA, since accuracy this does allow precise determination status.