Effects of tobacco smoking on neuropsychological function in schizophrenia in comparison to other psychiatric disorders and non-psychiatric controls.

摘要: Background and Objectives Compared to the general population cigarette smoking prevalence is elevated in psychiatric disorders such as schizophrenia (SZ), bipolar disorder (BD), major depressive (MDD). These are also associated with neurocognitive impairments. Cigarette improved cognition SZ. The effects of on BD MDD less well studied. Methods We used a cross-sectional design study neuropsychological performance these function status. Subjects (N = 108) were SZ smokers (n = 32), non-smokers (n = 15), (n = 10), (n = 6), control (n = 12), (n = 17). Participants completed battery; non-deprived. Results SZ subjects performed significantly worse than controls select domains, while did not differ from controls. Three verbal memory outcomes compared non-smokers; status alter or MDD. Conclusions Scientific Significance These data suggest that improvements SZ, but MDD. Our may specificity cigarette-smoking modulation deficits (Am J Addict 2013;22:46-53)