The Impact of Heart Irradiation on Dose–Volume Effects in the Rat Lung
作者： Peter van Luijk , Hette Faber , Harm Meertens , Jacobus M. Schippers , Johannes A. Langendijk
DOI: 10.1016/J.IJROBP.2007.05.065
关键词:
摘要: Purpose To test the hypothesis that heart irradiation increases risk of a symptomatic radiation-induced loss lung function (SRILF) and this can be well-described as modulation functional reserve lung. Methods Materials Rats were irradiated with 150-MeV protons. Dose–response curves obtained for significant increase in breathing frequency after 100%, 75%, 50%, or 25% total volume, either including excluding from field. A mean respiratory rate 6–12 weeks compared 0–4 was defined SRILF, based on biweekly measurements rate. The critical volume (CV) model used to describe SRILF. Fits done using maximum likelihood method. Consistency between data tested previously developed goodness-of-fit test. Results CV could fitted consistently only. However, failed predict also included irradiation. Even refitting all resulted difference data. These results imply that, although describes SRILF when is spared, needs modified account impact dose Finally, described consistent Conclusions detrimental effect incidence by dependent decrease
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Charles E. Metz, Basic principles of ROC analysis Seminars in Nuclear Medicine. ,vol. 8, pp. 283- 298 ,(1978) , 10.1016/S0001-2998(78)80014-2
Alena Novakova-Jiresova, Peter van Luijk, Harry van Goor, Harm H. Kampinga, Robert P. Coppes, Changes in Expression of Injury After Irradiation of Increasing Volumes in Rat Lung International Journal of Radiation Oncology Biology Physics. ,vol. 67, pp. 1510- 1518 ,(2007) , 10.1016/J.IJROBP.2006.11.058
L.J. Boersma, E.M.F. Damen, R.W. de Boer, S.H. Muller, R.A.Valdés Olmos, N. van Zandwijk, J.V. Lebesque, Estimation of overall pulmonary function after irradiation using dose-effect relations for local functional injury Radiotherapy and Oncology. ,vol. 36, pp. 15- 23 ,(1995) , 10.1016/0167-8140(95)01580-A
George Rodrigues, Michael Lock, David D'Souza, Edward Yu, Jake Van Dyk, Prediction of radiation pneumonitis by dose - volume histogram parameters in lung cancer--a systematic review. Radiotherapy and Oncology. ,vol. 71, pp. 127- 138 ,(2004) , 10.1016/J.RADONC.2004.02.015
Mary E. Charlson, Peter Pompei, Kathy L. Ales, C.Ronald MacKenzie, A new method of classifying prognostic comorbidity in longitudinal studies: Development and validation☆ Journal of Chronic Diseases. ,vol. 40, pp. 373- 383 ,(1987) , 10.1016/0021-9681(87)90171-8
Theodore J Robnett, Mitchell Machtay, Eugene F Vines, Michael G McKenna, Kenneth M Algazy, W.Gillies McKenna, Factors predicting severe radiation pneumonitis in patients receiving definitive chemoradiation for lung cancer International Journal of Radiation Oncology Biology Physics. ,vol. 48, pp. 89- 94 ,(1999) , 10.1016/S0360-3016(00)00648-9
Alena Novakova-Jiresova, Peter van Luijk, Harry van Goor, Harm H. Kampinga, Robert P. Coppes, Pulmonary Radiation Injury: Identification of Risk Factors Associated with Regional Hypersensitivity Cancer Research. ,vol. 65, pp. 3568- 3576 ,(2005) , 10.1158/0008-5472.CAN-04-3466
S. N. Boon, P. van Luijk, T. Böhringer, A. Coray, A. Lomax, E. Pedroni, B. Schaffner, J. M. Schippers, Performance of a fluorescent screen and CCD camera as a two-dimensional dosimetry system for dynamic treatment techniques Medical Physics. ,vol. 27, pp. 2198- 2208 ,(2000) , 10.1118/1.1289372
Michael A. Beckles, Stephen G. Spiro, Gene L. Colice, Robin M. Rudd, The Physiologic Evaluation of Patients With Lung Cancer Being Considered for Resectional Surgery Chest. ,vol. 123, pp. 1- 5 ,(2003) , 10.1378/CHEST.123.1_SUPPL.105S
Lawrence B. Marks, Michael T. Munley, Gunilla C. Bentel, Su-Min Zhou, Donna Hollis, Christopher Scarfone, Gregory S. Sibley, Feng-Ming Kong, Randy Jirtle, Ronald Jaszczak, R.Edward Coleman, Victor Tapson, Mitchell Anscher, Physical and biological predictors of changes in whole-lung function following thoracic irradiation International Journal of Radiation Oncology Biology Physics. ,vol. 39, pp. 563- 570 ,(1997) , 10.1016/S0360-3016(97)00343-X