Stimulants for the Control of Hedonic Appetite.

作者: Alison S. Poulton , Emily J. Hibbert , Bernard L. Champion , Ralph K. H. Nanan

DOI: 10.3389/FPHAR.2016.00105

关键词:

摘要: The focus of this paper is treatment obesity in relation to the management hedonic appetite. Obesity a complex condition which may be potentiated by excessive reward seeking combination with executive functioning deficits that impair cognitive control behavior. Stimulant medications address both deficiency and enhance motivation, as well suppressing They have long been recognized effective for treating obesity. However, stimulants can abused their euphoric effect. induce euphoria via same neural pathway underlies therapeutic effect For reason they generally not endorsed use Among stimulants, only phentermine (either alone or topiramate) bupropion (which has stimulant-like properties used naltrexone), are approved United States Food Drug Administration (FDA) obesity, although dexamphetamine methylpenidate widely attention deficit hyperactivity disorder (ADHD) adults children. Experience gained over many years ADHD demonstrates careful dose titration, safely. In improvement mood could assist lifestyle changes necessary weight control, acting synergistically appetite suppression. crisis reached stage strong consideration should given adequate utilization inexpensive class drug.

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