Successful recruitment of healthy African American men to genomic studies from high-volume community health fairs: implications for future genomic research in minority populations.

摘要: BACKGROUND: Study of genomic data obtained from patient biospecimens is frequent in research subjects with prostate and other epithelial malignancies. Understanding the characteristics healthy men who participate limited. METHODS: Patients were identified through Prostate Cancer Genetic Risk Evaluation SNPs Study Indiana University Biomarker Study, 2 population-based biomarker cohort studies. Between 2006 2010, Caucasian (n = 774) African American 381) recruited enrolled at high-volume free community health fairs. Each participant completed a demographic questionnaire provided blood sample for investigations. Frequency differences between features compared analyzed by 2-sample t test multivariate logistic regression after adjusting potential confounding variables significance P < .05 level. Features examined included: age, body mass index (BMI), income, education, marital status, tobacco, alcohol, family history, prostate-specific antigen (PSA) level, prior cancer screening history. RESULTS: Significant participating status (married, 69% vs 46% American, P< .001), mean age (years, 58 54 BMI (kg/m2, 30.9 32.3 .004), annual income (P .038), education .002), PSA (ng/mL, 1.2 2.0 .005). CONCLUSIONS: Significant exist choosing to research. These may be important designing study recruitment strategies. 2012;. © 2011 Society.