Salvianolic Acid Y: A New Protector of PC12 Cells against Hydrogen Peroxide-Induced Injury from Salvia officinalis
作者： Jun Gong , Aichun Ju , Dazheng Zhou , Dekun Li , Wei Zhou
DOI: 10.3390/MOLECULES20010683
关键词:
摘要: Salvianolic acid Y (TSL 1), a new phenolic with the same planar structure as salvianolic B, was isolated from Salvia officinalis. The structural elucidation and stereochemistry determination were achieved by spectroscopic chemical methods, including 1D, 2D-NMR (1H-1H COSY, HMQC HMBC) circular dichroism (CD) experiments. biosynthesis pathway of B 1) proposed based on analysis. protection PC12 cells injury induced H2O2 assessed in vitro using cell viability assay. protected 54.2%, which significantly higher than (35.2%).
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