A mortalization theory for the control of cell proliferation and for the origin of immortal cell lines
作者： Sydney Shall , Wilfred D. Stein
DOI: 10.1016/0022-5193(79)90371-0
关键词:
摘要: Abstract An increasing rate of cellular mortalization sets a limit to the proliferation fibroblast populations. Failure mechanism leads formation immortal clones cells. A possible molecular model for process is described.
elsevier.com
sci-hub.se 参考文章(18)
Martin Gm, Cellular aging--postreplicative cells. A review (Part II). American Journal of Pathology. ,vol. 89, pp. 513- 530 ,(1977)
P.Marlene Absher, R.G. Absher, W.D. Barnes, Genealogies of clones of diploid fibroblasts. Cinemicrophotographic observations of cell division patterns in relation to population age. Experimental Cell Research. ,vol. 88, pp. 95- 104 ,(1974) , 10.1016/0014-4827(74)90622-3
V.J. Cristofalo, Barbara B. Sharf, Cellular senescence and DNA synthesis. Thymidine incorporation as a measure of population age in human diploid cells. Experimental Cell Research. ,vol. 76, pp. 419- 427 ,(1973) , 10.1016/0014-4827(73)90394-7
G. Tarrant, T. Kirkwood, R Holliday, L. Huschtscha, Testing the commitment theory of cellular aging Science. ,vol. 198, pp. 366- 372 ,(1977) , 10.1126/SCIENCE.910134
A. Macieira-Coelho, J. Pontén, L. Philipson, The division cycle and RNA-synthesis in diploid human cells at different passage levels in vitro. Experimental Cell Research. ,vol. 42, pp. 673- 684 ,(1966) , 10.1016/0014-4827(66)90280-1
J. R. Smith, L. Hayflick, VARIATION IN THE LIFE-SPAN OF CLONES DERIVED FROM HUMAN DIPLOID CELL STRAINS Journal of Cell Biology. ,vol. 62, pp. 48- 53 ,(1974) , 10.1083/JCB.62.1.48
A. MACIEIRA-COELHO, Are non-dividing cells present in ageing cell cultures? Nature. ,vol. 248, pp. 421- 422 ,(1974) , 10.1038/248421A0
L. Hayflick, P.S. Moorhead, The serial cultivation of human diploid cell strains. Experimental Cell Research. ,vol. 25, pp. 585- 621 ,(1961) , 10.1016/0014-4827(61)90192-6
RA Vincent Jr, PC Huang, None, The proportion of cells labeled with tritiated thymidine as a function of population doubling level in cultures of fetal, adult, mutant, and tumor origin Experimental Cell Research. ,vol. 102, pp. 31- 42 ,(1976) , 10.1016/0014-4827(76)90296-2
RAM PARSHAD, KATHERINE K. SANFORD, Intermittent exposure to fluorescent light extends lifespan of human diploid fibroblasts in culture. Nature. ,vol. 268, pp. 736- 737 ,(1977) , 10.1038/268736A0