Amantadine does not have antiviral activity against Borna disease virus
作者： B. Cubitt , J. JC. de la Torre
关键词:
摘要: We have investigated the antiviral activity of amantadine (AD) against Borna disease virus (BDV) in several culture cell systems. present evidence that AD, range 5 to 10 μM, does not BDV. Treatment BDV infected cells with AD for six days caused neither a reduction number cells, nor decrease steady state levels RNA or proteins. Moreover, treatment prior infection did affect multiplication, whereas influenza A yield was less than 1% respect obtained untreated control cells.
springer.com
sci-hub.se 参考文章(16)
J Kornhuber, M Weller, K Schoppmeyer, P Riederer, Amantadine and memantine are NMDA receptor antagonists with neuroprotective properties. Journal of Neural Transmission-supplement. ,vol. 43, pp. 91- 104 ,(1994)
C Sauder, A Müller, B Cubitt, J Mayer, J Steinmetz, W Trabert, B Ziegler, K Wanke, N Mueller-Lantzsch, J C de la Torre, F A Grässer, Detection of Borna disease virus (BDV) antibodies and BDV RNA in psychiatric patients: evidence for high sequence conservation of human blood-derived BDV RNA. Journal of Virology. ,vol. 70, pp. 7713- 7724 ,(1996) , 10.1128/JVI.70.11.7713-7724.1996
B Cubitt, C Oldstone, J C de la Torre, Sequence and genome organization of Borna disease virus. Journal of Virology. ,vol. 68, pp. 1382- 1396 ,(1994) , 10.1128/JVI.68.3.1382-1396.1994
T. Briese, A. Schneemann, A. J. Lewis, Y. S. Park, S. Kim, H. Ludwig, W. I. Lipkin, Genomic organization of Borna disease virus Proceedings of the National Academy of Sciences of the United States of America. ,vol. 91, pp. 4362- 4366 ,(1994) , 10.1073/PNAS.91.10.4362
Robert S. Schwab, Amantadine in Parkinson's Disease JAMA. ,vol. 222, pp. 792- 795 ,(1972) , 10.1001/JAMA.1972.03210070026008
Juan Carlos de la Torre, Daniel Gonzalez-Dunia, Beatrice Cubitt, Margaret Mallory, Nikolaus Mueller-Lantzsch, Friedrich A. Grässer, Lawrence A. Hansen, Eliezer Masliah, DETECTION OF BORNA DISEASE VIRUS ANTIGEN AND RNA IN HUMAN AUTOPSY BRAIN SAMPLES FROM NEUROPSYCHIATRIC PATIENTS Virology. ,vol. 223, pp. 272- 282 ,(1996) , 10.1006/VIRO.1996.0479
Klaus Lieb, Frank T Hufert, Karl Bechter, Joachim Bauer, Johannes Kornhuber, Depression, Borna disease, and amantadine The Lancet. ,vol. 349, pp. 958- ,(1997) , 10.1016/S0140-6736(05)62741-9
Anette Schneemann, Patrick A. Schneider, Robert A. Lamb, W.Ian Lipkin, The remarkable coding strategy of borna disease virus: a new member of the nonsegmented negative strand RNA viruses. Virology. ,vol. 210, pp. 1- 8 ,(1995) , 10.1006/VIRO.1995.1311
Royce W. Waltrip, Robert W. Buchanan, Ann Summerfelt, Alan Breier, William T. Carpenter, Nancy L. Bryant, Steven A. Rubin, Kathryn M. Carbone, Borna disease virus and schizophrenia Psychiatry Research-neuroimaging. ,vol. 56, pp. 33- 44 ,(1995) , 10.1016/0165-1781(94)02600-N
Liv Bode, Wolfgang Zimmermann, Ron Ferszt, Falko Steinbach, Hanns Ludwig, Borna disease virus genome transcribed and expressed in psychiatric patients. Nature Medicine. ,vol. 1, pp. 232- 236 ,(1995) , 10.1038/NM0395-232