Human papillomavirus prevalence and type distribution among women attending routine gynecological examinations in Saudi Arabia

摘要: Cervical cancer (CC) is caused by persistent infection with high-risk (HR) human papillomavirus (HPV) types. In Saudi Arabia which has a population of 6.5 million women over the age 15 years, approximately 152 new cases CC are diagnosed and 55 die from disease annually. Nevertheless current epidemiological data for HPV in this limited. This study evaluated prevalence type distribution documented awareness health-related behavior among non-Saudi attending routine examination. was an observational, cross-sectional conducted between April 2010 December 2011 at three hospitals Arabia. samples aged ≥15 years, who were gynecological examinations collected tested HPV-DNA polymerase chain reaction typed using SPF10 DEIA/LiPA25 system. Two questionnaires on completed. A total 417 women, mean (standard deviation) 41.9 (±10.4) years, included final analysis, whom 77% (321/417) nationals. detected 9.8% (41/417, 95% confidence interval [CI]: 7.1-13.1). The any HR-HPV was: 25–34 years: 3.0%; 35–44 4.5%; 45–54 3.2%; >55 years: 10.9%. most prevalent HR-HPV-types were: HPV-68/73 (5 cases); HPV-18 (4 HPV-16 (3 cases). low risk (LR) types HPV-6 HPV-42, HPV-53 HPV-54 (2 each). higher nationals vs. (16.7% 7.8%, P = 0.0234). No statistically significant factors identified: 32.2% (101/314) aware 89.9% (285/317) showed interest vaccination. overall Arabia, but 55 years, as well These provide reference public health authorities may also help determining future policies prevention CC. NCT01213459