Cervical Cancer and Genital Infections: Assessment of Performance and Validation in Human Papillomavirus Genotyping Assays in Iran, its Neighbouring Countries and Persian Gulf Area

摘要: Background: The accuracy of diagnostic assays in Human Papillomavirus (HPV) genital infection and cervical cancer has remained a clinical challenge diagnosis.  Evidence indicates that large proportion can be prevented through organized care for HPV testing. Countries with low per capita income, such as Iran its neighbours, have no national program screening vaccination. aim this study was to review recent published papers region evaluating the efficacy released data regarding genotyping system infections Methods: Investigating various medical search engines retrieved 46 reports, mostly after 2010, consisting either home brew protocols or commercial technologies field. Results: Summarized results demonstrated except few cases, all reports were limited studies performed confined populations focusing on attending patients at clinics regular checkups. In present study, 52.8% from rest belonged other countries. rate reported range 0.62% 25% normal population, while it varied 18.75% 100% females cancer. surveys, only 26.1 % (12/46) had validated World Health Organization (WHO) proficient procedures. Also, multiple not mentioned 56.52% (25/46) researches. Conclusions: Employing reliable methods is best way related precancerous diseases these areas. focus most surveys come up policies establishing preventive Persian Gulf area.