CAMTA1 is a novel tumour suppressor regulated by miR-9/9*in glioblastoma stem cells

作者: Daniel Schraivogel , Lasse Weinmann , Dagmar Beier , Ghazaleh Tabatabai , Alexander Eichner

DOI: 10.1038/EMBOJ.2011.301

关键词:

摘要: … in glioblastoma. Consistently, we find that CAMTA1 expression correlates with glioblastoma … Data were obtained from the REMBRANDT and the TCGA databases (see Materials and …

参考文章(70)
Daniela Wübbenhorst, Dipl Biol, Katja Dumler, Dipl Ing, Bettina Wagner, Gabriele Wexel, Andreas Imhoff, Bernd Gansbacher, Stephan Vogt, Martina Anton, Tetracycline-regulated bone morphogenetic protein 2 gene expression in lentivirally transduced primary rabbit chondrocytes for treatment of cartilage defects. Arthritis & Rheumatism. ,vol. 62, pp. 2037- 2046 ,(2010) , 10.1002/ART.27461
Dvora Nass, Shai Rosenwald, Eti Meiri, Shlomit Gilad, Hilla Tabibian-Keissar, Anat Schlosberg, Hagit Kuker, Netta Sion-Vardy, Ana Tobar, Oleg Kharenko, Einat Sitbon, Gila Lithwick Yanai, Eran Elyakim, Hila Cholakh, Hadas Gibori, Yael Spector, Zvi Bentwich, Iris Barshack, Nitzan Rosenfeld, MiR-92b and miR-9/9* Are Specifically Expressed in Brain Primary Tumors and Can Be Used to Differentiate Primary from Metastatic Brain Tumors Brain Pathology. ,vol. 19, pp. 375- 383 ,(2009) , 10.1111/J.1750-3639.2008.00184.X
Tae-Min Kim, Wei Huang, Richard Park, Peter J. Park, Mark D. Johnson, A Developmental Taxonomy of Glioblastoma Defined and Maintained By MicroRNAs Cancer Research. ,vol. 71, pp. 3387- 3399 ,(2011) , 10.1158/0008-5472.CAN-10-4117
Michaela Beitzinger, Lasse Peters, Jia Yun Zhu, Elisabeth Kremmer, Gunter Meister, Identification of human microRNA targets from isolated argonaute protein complexes. RNA Biology. ,vol. 4, pp. 76- 84 ,(2007) , 10.4161/RNA.4.2.4640
Jason T. Huse, Heidi S. Phillips, Cameron W. Brennan, Molecular subclassification of diffuse gliomas: seeing order in the chaos. Glia. ,vol. 59, pp. 1190- 1199 ,(2011) , 10.1002/GLIA.21165
Dagmar Beier, Peter Hau, Martin Proescholdt, Annette Lohmeier, Jörg Wischhusen, Peter J. Oefner, Ludwig Aigner, Alexander Brawanski, Ulrich Bogdahn, Christoph P. Beier, CD133(+) and CD133(-) glioblastoma-derived cancer stem cells show differential growth characteristics and molecular profiles. Cancer Research. ,vol. 67, pp. 4010- 4015 ,(2007) , 10.1158/0008-5472.CAN-06-4180
Jane E. Visvader, Geoffrey J. Lindeman, Cancer stem cells in solid tumours: accumulating evidence and unresolved questions Nature Reviews Cancer. ,vol. 8, pp. 755- 768 ,(2008) , 10.1038/NRC2499
Chunnian Zhao, GuoQiang Sun, Shengxiu Li, Yanhong Shi, A feedback regulatory loop involving microRNA-9 and nuclear receptor TLX in neural stem cell fate determination Nature Structural & Molecular Biology. ,vol. 16, pp. 365- 371 ,(2009) , 10.1038/NSMB.1576
A. N. Packer, Y. Xing, S. Q. Harper, L. Jones, B. L. Davidson, The bifunctional microRNA miR-9/miR-9* regulates REST and CoREST and is downregulated in Huntington's disease. The Journal of Neuroscience. ,vol. 28, pp. 14341- 14346 ,(2008) , 10.1523/JNEUROSCI.2390-08.2008
P Mestdagh, E Fredlund, F Pattyn, J H Schulte, D Muth, J Vermeulen, C Kumps, S Schlierf, K De Preter, N Van Roy, R Noguera, G Laureys, A Schramm, A Eggert, F Westermann, F Speleman, J Vandesompele, MYCN/c-MYC-induced microRNAs repress coding gene networks associated with poor outcome in MYCN/c-MYC-activated tumors Oncogene. ,vol. 29, pp. 1394- 1404 ,(2010) , 10.1038/ONC.2009.429