In Vitro and In Vivo Evaluation of Potential Toxicity of Industrial Particles
作者： Catherine Aranyi , Jeannie Bradof , Donald E. Gardner , Joellen Lewtas Huisingh
DOI: 10.1007/978-1-4684-4121-5_32
关键词:
摘要: Alveolar macrophages (AM) protect the lungs by phagocytosis and digestion of inhaled irritant particles infectious agents. Reduced activity AM system can impair lung’s defensive capacity increase susceptibility to respiratory disease. Since resistance infection may be lowered exposure an inhalation hazard, changes in major functional characteristics used monitor environmental stresses intact animal. In addition, since these cells obtained easily tracheobronchial lavage maintained culture, they are frequently vitro cellular toxicology assess potential hazard various substances.
springer.com
sci-hub.st 参考文章(9)
Michael D. Waters, Joellen L. Huisingh, Neil E. Garrett, The Cellular Toxicity of Complex Environmental Mixtures Springer, Boston, MA. pp. 125- 167 ,(1978) , 10.1007/978-1-4684-3611-2_6
S.D. Lee, J.B. Mudd, Assessing toxic effects of environmental pollutants Ann Arbor Science,Ann Arbor, MI. ,(1980)
R Ehrlich, Effect of nitrogen dioxide on resistance to respiratory infection. Bacteriological Reviews. ,vol. 30, pp. 604- 614 ,(1966) , 10.1128/BR.30.3.604-614.1966
Michael D. Waters, Donald E. Gardner, Catherine Aranyi, David L. Coffin, Metal toxicity for rabbit alveolar macrophages in vitro Environmental Research. ,vol. 9, pp. 32- 47 ,(1975) , 10.1016/0013-9351(75)90047-X
Catherine Aranyi, Frederick J. Miller, Sandra Andres, Richard Ehrlich, James Fenters, Donald E. Gardner, Michael D. Waters, Cytotoxicity to alveolar macrophages of trace metals adsorbed on fly ash. Environmental Research. ,vol. 20, pp. 14- 23 ,(1979) , 10.1016/0013-9351(79)90081-1
Michael D. Waters, Donald E. Gardner, David L. Coffin, Cytotoxic effects of vanadium on rabbit alveolar macrophages in vitro Toxicology and Applied Pharmacology. ,vol. 28, pp. 253- 263 ,(1974) , 10.1016/0041-008X(74)90012-X
Green Gm, Goldstein E, A method for quantitating intrapulmonary bacterial inactivation in individual animals. Journal of Laboratory and Clinical Medicine. ,vol. 68, pp. 669- 677 ,(1966)
R Ehrlich, Effect of nitrogen dioxide on resistance to respiratory infection. Bacteriological Reviews. ,vol. 30, pp. 604- 614 ,(1966) , 10.1128/MMBR.30.3.604-614.1966