Zymosan-induced chemiluminescence of alveolar macrophages: depression by inorganic dust constituents.
作者： Maria Labedzka , Holger Gulyas , Guenther Gercken
DOI: 10.1007/BF01055555
关键词:
摘要: A method has been developed which allows the incubation of alveolar macrophages as weakly affixed monolayers in siliconized glass dishes. Without vigorous mechanical agitation and without using proteolytic enzymes, these cells were subsequently transferred to cuvettes where zymosan-stimulated chemiluminescence suspended was measured.In vitro incubations activated rabbit macrophage with airborne dusts from four West German sites (1 200 μg/106 cells), fly ash fractions a special waste incinerator at Hamburg (50 1,000 quartz dust DQ 12 (5 cells) resulted dose-dependent depression chemiluminescence. The correlated particle numbers, estimated surface, antimony lead masses exposed. Cytotoxicity better parameters than mass.
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