Toward an effective strategy in glioblastoma treatment. Part I: resistance mechanisms and strategies to overcome resistance of glioblastoma to temozolomide

作者: Khaled Messaoudi , Anne Clavreul , Frédéric Lagarce

DOI: 10.1016/J.DRUDIS.2015.02.011

关键词:

摘要: Glioblastoma multiforme (GBM) is a devastating disease and the most lethal of adult brain tumors. Treatment is based on surgery, radiotherapy and chemotherapy by oral …

参考文章(80)
Ralf F. Pettersson, A. Jonas Ekstrand, C. David James, V. Peter Collins, V. Peter Collins, Barbara Seliger, Webster K. Cavenee, Genes for Epidermal Growth Factor Receptor, Transforming Growth Factor α, and Epidermal Growth Factor and Their Expression in Human Gliomas in Vivo Cancer Research. ,vol. 51, pp. 2164- 2172 ,(1991)
Marie Le Mercier, Shannon Fortin, Véronique Mathieu, Robert Kiss, Florence Lefranc, Galectins and gliomas. Brain Pathology. ,vol. 20, pp. 17- 27 ,(2010) , 10.1111/J.1750-3639.2009.00270.X
Lili Liu, Sanford Markowitz, Stanton L. Gerson, Mismatch repair mutations override alkyltransferase in conferring resistance to temozolomide but not to 1,3-bis(2-chloroethyl)nitrosourea. Cancer Research. ,vol. 56, pp. 5375- 5379 ,(1996)
Kathleen R. Lamborn, Ken D. Aldape, Jane Uyehara-Lock, Joon Uhm, Sandra Passe, Mitchel Berger, Michael Prados, Brian P. O’Neill, Eric C. Burton, Robert B. Jenkins, James Scott, Jason O’Campo, Peter Forsyth, Aberrant p53, mdm2, and proliferation differ in glioblastomas from long-term compared with typical survivors. Clinical Cancer Research. ,vol. 8, pp. 180- 187 ,(2002)
Louis M. Weiner, Rishi Surana, Shangzi Wang, Monoclonal antibodies: versatile platforms for cancer immunotherapy Nature Reviews Immunology. ,vol. 10, pp. 317- 327 ,(2010) , 10.1038/NRI2744
Natalia Rubinstein, Mariano Alvarez, Norberto W Zwirner, Marta A Toscano, Juan M Ilarregui, Alicia Bravo, José Mordoh, Leonardo Fainboim, Osvaldo L Podhajcer, Gabriel A Rabinovich, Targeted inhibition of galectin-1 gene expression in tumor cells results in heightened T cell-mediated rejection; A potential mechanism of tumor-immune privilege. Cancer Cell. ,vol. 5, pp. 241- 251 ,(2004) , 10.1016/S1535-6108(04)00024-8
Bernd Kaina, Markus Christmann, Steffen Naumann, Wynand P. Roos, MGMT: key node in the battle against genotoxicity, carcinogenicity and apoptosis induced by alkylating agents. DNA Repair. ,vol. 6, pp. 1079- 1099 ,(2007) , 10.1016/J.DNAREP.2007.03.008
Marie Le Mercier, Florence Lefranc, Tatjana Mijatovic, Olivier Debeir, Benjamin Haibe-Kains, Gianluca Bontempi, Christine Decaestecker, Robert Kiss, Véronique Mathieu, Evidence of galectin-1 involvement in glioma chemoresistance. Toxicology and Applied Pharmacology. ,vol. 229, pp. 172- 183 ,(2008) , 10.1016/J.TAAP.2008.01.009
Margaret S Ebert, Joel R Neilson, Phillip A Sharp, MicroRNA sponges: competitive inhibitors of small RNAs in mammalian cells Nature Methods. ,vol. 4, pp. 721- 726 ,(2007) , 10.1038/NMETH1079