Characterization and evaluation of silver release from four different dressings used in burns care
作者： Chiara Rigo , Marco Roman , Ivan Munivrana , Vincenzo Vindigni , Bruno Azzena
DOI: 10.1016/J.BURNS.2012.06.013
关键词:
摘要: For centuries silver and compounds have been in use to control infection avoid septicaemia the care of burns chronic wounds. Renewed interest has resulted a number Ag based dressings that are now widely used centres. Despite extensive use, systematic study chemical composition, release kinetics biochemical action these products yet be published. In this work we characterized morphology four commercial by scanning electron microscopy content was determined range between 1.39 mg/cm(2) 0.03 mg/cm(2). Release three different matrices (ultra pure water, normal saline solution human serum substitute) were determined. The highest rates found substitute, with maximum 4099 μg/(hcm(2)) minimum 0.0001 μg/(hcm(2)). Our results show mean inhibitory concentrations exceeded for most common pathogens substitute sterile but presence high Cl(-) tend inactivate dressings.
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