ArnS, a kinase involved in starvation-induced archaellum expression

摘要: Organisms have evolved motility organelles that allow them to move favorable habitats. Cells integrate environmental stimuli into intracellular signals machineries direct this migration. Many are complex surface appendages a tight, hierarchical regulation of expression. In the crenearchaeon Sulfolobus acidocaldarius, biosynthesis archaellum is regulated by regulatory network proteins control expression components in phosphorylation-dependent manner. A major trigger for nutrient starvation, but although some known, cascade triggered starvation poorly understood. work, we identify starvation-induced Ser/Thr protein kinase ArnS (Saci_1181) which located proximally operon. Deletion arnS results reduced motility, though properly assembled. Therefore, our experimental and modelling indicate plays an essential role precisely controlled during acidocaldarius. Furthermore combine vivo experiments mathematical models describe first time archaea dynamics key regulators This article protected copyright. All rights reserved.