Influence of Donor Age on the Biomechanical and Biochemical Properties of Human Meniscal Allografts

摘要: BackgroundAlthough the use of meniscal allografts to replace severely damaged or absent menisci is commonplace, little known about effects donor age on biochemical and biomechanical properties human menisci.HypothesisThe mechanical medial lateral from donors less than 45 years do not vary with age.Study DesignControlled laboratory study.MethodsThirty-three 25 34 (26 male 8 female) ranging 15 44 were harvested immediately stored at —80°C. The outer third each meniscus was subjected static dynamic tensile analysis. In addition, composition (collagen, proteoglycan, water content) these samples analyzed.ResultsThere no correlation between stiffness for either (R2 = .003) .002) meniscus. Likewise, there modulus for...