Clinical Trypanosoma rangeli infection as a complication of Chagas' disease.

摘要: Laboratory studies on a group of 20 patients from the Rio Negro Valley, Colombia selected for detailed study showed that 14 gave antibody reactions immunoassay consistent with Trypanosoma cruzi or T. rangeli infections. Four were diagnosed as having infection, 4 had mixed infections and 6 infected alone. Immunoprecipitation analysis sera cruzi-infected recognized similar range trypomastigote-derived polypeptides in Brazil, all Colombian reacted 160 kiloDalton (kDa) polypeptide associated active infection. Although infection alone positive immunofluorescence ELISA reaction rangeli, they failed to bind parasite by either immunoprecipitation Western blotting. Intriguingly, consistently stronger, but qualitatively similar, binding blotting compared