Effect of β -cyclodextrin on the aggregation of the non-ionic surfactant Igepal CO-630 in water as studied by 1D and 2D NMR spectroscopy

摘要: The micellization process of the non-ionic surfactant, Igepal CO-630, and its inclusion complexes with β-cyclodextrin (β-CD) have been investigated by NMR spectroscopy. critical micelle concentration was determined measuring chemical shifts different resonances. structure binding between β-CD studied 1D proton ROESY experiments. stoichiometry complex is mainly 1:1, a slight contribution 2:1. At high concentrations plots in absence presence coalesce, which indicates that do not take part into micelles. spectrum displays strong correlations internal cavity protons CD aromatic aliphatic regions Igepal, suggesting formation 2:1 primary face-to-face at β-CD.