Long-term clinical consequences of acute kidney injury in the HIV-infected

作者: Andy I. Choi , Yongmei Li , Chirag Parikh , Paul A. Volberding , Michael G. Shlipak

DOI: 10.1038/KI.2010.171

关键词:

摘要: To evaluate the long-term consequences of acute kidney injury (AKI) in human immunodeficiency virus (HIV)-infected persons, we studied 17,325 patients a national HIV registry during their first hospitalization. We determined association AKI with risk for heart failure, cardiovascular events, end-stage renal disease (ESRD), and mortality beginning 90 days after discharge. Based on Network criteria, 2453 had stage 1; 273 2 or 3; 334 dialysis-requiring AKI. Over mean follow-up period 5.7 years, 333 673 diseases (CVDs), 348 developed ESRD, 8405 deaths occurred. In multivariable-adjusted analyses, 1 was associated death but not failure other CVD. Dialysis-requiring much stronger significant associations increased addition to events. When reclassified account recovery, recovery still death, ESRD. Thus, this sample HIV-infected found clinical repercussions appear extend beyond hospital setting contributing excess risks, mortality. Additionally, affected almost one six who survived at least following

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