The molecular genetics of holoprosencephaly: a model of brain development for the next century
作者： Erich Roessler , M. Muenke
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摘要: The recent identification of some the human holoprosencephaly genes is beginning to elucidate intricate developmental programs that pattern normal and abnormal brain development. Here we present these advances in context our understanding conclude with speculations regarding direction for future investigations. We are living a tremendously exciting time medicine rapid application molecular genetic approaches disease. It purpose this review stress underlying principals approach at level can be readily appreciated by colleagues who themselves experts anatomy but not necessarily genetics
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