Irradiation, chemotherapy and surgery in esophageal cancer: A randomized clinical study
作者： A.P. Andersen , P. Berdal , F. Edsmyr , S. Hagen , R. Hatlevoll
DOI: 10.1016/S0167-8140(84)80058-4
关键词:
摘要: Summary In a randomized trial, irradiation alone (35 Gy) or (30 and bleomycin was given as preoperative treatment of esophageal cancer. inoperable patients, split course (63 (55 given. Bleomycin doses were 5 mg i.m.1/2−1 h before each dose. No benefit obtained by addition to concerning survival palliation dysphagia. seen either in any subgroup patients according different primary tumour classifications, histopathological gradings localizations tumour. with advanced/metastatic disease, adriamycin gave significantly longer than alone. It shown that the presence T 1 tumours significant prognostic factor for long-term performing radical operation advantage survival. Female treated without survived males, but operable there no difference between two sexes regard
sci-hub.se 参考文章(16)
Richard Peto, M. C. Pike, Conservatism of the approximation sigma (O-E)2-E in the logrank test for survival data or tumor incidence data. Biometrics. ,vol. 29, pp. 579- 584 ,(1973) , 10.2307/2529177
Richard D. Marks, Hugh J. Scruggs, Keene M. Wallace, Preoperative radiation therapy for carcinoma of the esophagus Cancer. ,vol. 38, pp. 84- 89 ,(1976) , 10.1002/1097-0142(197607)38:1<84::AID-CNCR2820380115>3.0.CO;2-S
Edward F. Parker, Carcinoma of the Esophagus JAMA. ,vol. 235, pp. 1018- 1020 ,(1976) , 10.1001/JAMA.1976.03260360020018
Ichiro Akakura, Yoshizo Nakamura, Temo Kakegawa, Ryuichi Nakayama, Hiroshi Watanabe, Hisao Yamashita, Surgery of carcinoma of the esophagus with preoperative radiation. Chest. ,vol. 57, pp. 47- 57 ,(1970) , 10.1378/CHEST.57.1.47
Krsto Kolarić, Zeljko Maričić, Anton Roth, Ivo Dujmović, Combination of bleomycin and adriamycin with and without radiation in the treatment of inoperable esophageal cancer. A randomized study Cancer. ,vol. 45, pp. 2265- 2273 ,(1980) , 10.1002/1097-0142(19800501)45:9<2265::AID-CNCR2820450908>3.0.CO;2-7
Richard Earlam, J. R. Cunha-Melo, Oesophageal squamous cell carcinoma: II. A critical review of radiotherapy† British Journal of Surgery. ,vol. 67, pp. 457- 461 ,(2005) , 10.1002/BJS.1800670702
Sidney Siegel, Nonparametric statistics for the behavioral sciences ,(1956)
Richard Earlam, J. R. Cunha-Melo, Oesophageal squamous cell carcinoma: I. A critical review of surgery British Journal of Surgery. ,vol. 67, pp. 381- 390 ,(2005) , 10.1002/BJS.1800670602
J. Kirk, W.M. Gray, E.R. Watson, Cumulative radiation effect part I: Fractionated treatment regimes Clinical Radiology. ,vol. 22, pp. 145- 155 ,(1971) , 10.1016/S0009-9260(71)80044-2
Frank Ellis, Dose, time and fractionation: A clinical hypothesis Clinical Radiology. ,vol. 20, pp. 1- 7 ,(1969) , 10.1016/S0009-9260(69)80043-7