Evolución de la Coqueluche en la Argentina a finales del siglo XX

摘要: The objective of this study was to analize data pertussis morbidity and mortality in Argentina vaccination coverage with combined vaccine (DwPT), which available from 1969 until 2000 inclusive, investigate their interrelation. A retrospective performed based on National Registers. Notification annual mean variation rates geometric rates, by periods, were analyzed, correlation coefficients between each one them calculated. for 1969-2000 -14.34 1980-2000 -17.26; -10.41. Vaccination infants up year age (3 doses) 44.4% 1980; less than 60% 1982 higher 80% after 1990. highly significant inverse observed, (a) implementation, increase its coverage, introduction a fifth dose, (b) notification rates. It observed during the study, that our country there is relatively little knowledge about disease occurrence adults, an apparent absence population-based studies efficacy erythromycin chemo prophylaxis epidemics outbreaks. Based these data, strategies better surveillance control pertussis, are exposed.