The prevalence of hepatitis C virus infection in thalassemia patients in Iran from 2000 to 2017: a systematic review and meta-analysis.
作者： Masoud Behzadifar , Hassan Abolghasem Gorji , Nicola Luigi Bragazzi
DOI: 10.1007/S00705-018-3767-0
关键词:
摘要: One of the major infections transmitted through bloodstream is hepatitis C virus (HCV) infection. Patients with thalassemia requiring frequent blood transfusions are at risk for HCV. Therefore, this study was conducted to determine incidence HCV in patients Iran. The following databases were searched: ISI/Web Science, Embase, Pubmed/MEDLINE via Ovid, Scopus, as well Iranian (Magiran, Irandoc and SID) from January 2000 July 2017. quality studies evaluated using 22-item STROBE checklist. random model based on DerSimonian/Laird approach used. To assess stability results, a sensitivity analysis performed, stratifying basis quality, sample size, year publication, geographical area studies. Also, meta-regression analyses carried out terms size publication Fifty-two included. total number included 13,291. Based model, overall prevalence 19% (95% CI 16-21). results did not differ before after analysis. Iran 19%. This figure lower than neighboring countries Screening use diagnostic methods screening donors essential. In addition, treatment should be seriously addressed by agenda health system.
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