Prevalence of hepatitis C virus, hepatitis B virus, human immunodeficiency virus and related risk factors among hemophilia and thalassemia patients In Iran

作者: Ahmad Mirzabaghi , Zahra Shahshahan , Hamid Kalantari , Mojtaba Akbari

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摘要: Objectives: This study was conducted to assess the prevalence of Hepatitis C virus (HCV), B (HBV) and Human immunodeficiency (HIV) among hemophilia thalassemia patients. Patients Methods: Present from October 2008 December 2010 in Isfahan, Iran. One thousand one hundred sixty adult multi-transfused patients (822 males, 338 females, mean age 22.7±11.5 years) suffering beta-thalassemia (n = 545) (n=615) were enrolled study. Blood samples obtained tested for HBs Ag, Anti-HCV Ag Anti- HIV Ab. HCV positive underwent genotype determination. Results: Of 545 patients, 312(57.2%) male 233 (42.8%) female. From 615 511(83%) 104 (17%) Chronic hepatitis detected 505(82.1%) which 495 (98%) Ab 10 (2%) had HBsAg positive. The 56 (11%) with chronic 50 (89.2%) 6 (10.8%) respectively. None History family is major risk factors 1 our Conclusion: concern strategies prevention HCV, HBV safety blood products this respect have indeed been successful. Keywords: Transfusion, Blood-borne pathogens, hepatitis, Thalassemia, Hemophilia.

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