Decreased mRNA expression of the PTH/PTHrP receptor and type II sodium-dependent phosphate transporter in the kidney of rats fed a high phosphorus diet accompanied with a decrease in serum calcium concentration.
作者： Shin-ichi KATSUMATA , Ritsuko MASUYAMA , Mariko UEHARA , Kazuharu SUZUKI
DOI: 10.1271/BBB.68.2484
关键词:
摘要: This study investigates the phosphorus (P) homeostasis in process of an altered parathyroid hormone (PTH) action kidney rats fed a high P diet. Four-week-old male Wistar strain were diets containing five different levels (0.3, 0.6, 0.9, 1.2 and 1.5%) for 21 days. The serum PTH concentration urinary excretion elevated with increasing dietary level. Compared to 0.3% diet, calcium (Ca) remained unchanged, while 1,25(OH)2D3 cAMP level 0.6–0.9% P. On other hand, lower Ca was observed 1.2% or greater unchanged P, comparison PTH/PTH-related peptide (PTHrP) receptor type II...
oup.com
sci-hub.se 参考文章(21)
Elizabeth G Gimblet, Amy F Marney, Roy W Bonsnes, Determination of Calcium and Magnesium in Serum, Urine, Diet, and Stool by Atomic Absorption Spectrophotometry Clinical Chemistry. ,vol. 13, pp. 204- 214 ,(1967) , 10.1093/CLINCHEM/13.3.204
A. Werner, S.A. Kempson, J. Biber, H. Murer, Increase of Na/Pi-cotransport encoding mRNA in response to low Pi diet in rat kidney cortex. Journal of Biological Chemistry. ,vol. 269, pp. 6637- 6639 ,(1994) , 10.1016/S0021-9258(17)37420-3
Philip G. Reeves, Forrest H. Nielsen, George C. Fahey, AIN-93 Purified Diets for Laboratory Rodents: Final Report of the American Institute of Nutrition Ad Hoc Writing Committee on the Reformulation of the AIN-76A Rodent Diet Journal of Nutrition. ,vol. 123, pp. 1939- 1951 ,(1993) , 10.1093/JN/123.11.1939
MONA S. CALVO, RAJIV KUMAR, HUNTER HEATH, Persistently Elevated Parathyroid Hormone Secretion and Action in Young Women after Four Weeks of Ingesting High Phosphorus, Low Calcium Diets* The Journal of Clinical Endocrinology and Metabolism. ,vol. 70, pp. 1334- 1340 ,(1990) , 10.1210/JCEM-70-5-1334
Ritsuko Masuyama, Mariko Uehara, Kazuharu Suzuki, Shiro Goto, The action of magnesium in reducing renal calcification in rats receiving high phosphorus supplemented diet Nutrition Research. ,vol. 15, pp. 1673- 1682 ,(1995) , 10.1016/0271-5317(95)02038-0
M Janulis, M S Wong, M J Favus, Structure-function requirements of parathyroid hormone for stimulation of 1,25-dihydroxyvitamin D3 production by rat renal proximal tubules Endocrinology. ,vol. 133, pp. 713- 719 ,(1993) , 10.1210/ENDO.133.2.8344210
K. Katai, H. Segawa, H. Haga, K. Morita, H. Arai, S. Tatsumi, Y. Taketani, K.-i. Miyamoto, S. Hisano, Y. Fukui, E. Takeda, Acute Regulation by Dietary Phosphate of the Sodium-Dependent Phosphate Transporter (NaP1-2) in Rat Kidney Journal of Biochemistry. ,vol. 121, pp. 50- 55 ,(1997) , 10.1093/OXFORDJOURNALS.JBCHEM.A021569
Ritsuko MASUYAMA, Mariko UEHARA, Kazuharu SUZUKI, High P diet induces acute secretion of parathyroidhormone without alteration of serum calcium levels in rats. Bioscience, Biotechnology, and Biochemistry. ,vol. 64, pp. 2316- 2319 ,(2000) , 10.1271/BBB.64.2316
Shin-ichi KATSUMATA, Ritsuko MASUYAMA, Moyuru KOSHIHARA, Hiroshi MATSUZAKI, Mariko UEHARA, Kazuharu SUZUKI, High phosphorus diet changes phosphorus metabolism regardless of PTH action in rats Bioscience, Biotechnology, and Biochemistry. ,vol. 68, pp. 243- 246 ,(2004) , 10.1271/BBB.68.243
P Ureña, X F Kong, A B Abou-Samra, H Jüppner, H M Kronenberg, J T Potts, G V Segre, Parathyroid hormone (PTH)/PTH-related peptide receptor messenger ribonucleic acids are widely distributed in rat tissues. Endocrinology. ,vol. 133, pp. 617- 623 ,(1993) , 10.1210/ENDO.133.2.8393771