作者: Nanette K. Wenger
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摘要: Several converging issues have served to highlight the interest in postmenopausal hormone therapy as a coronary preventive intervention for women. First is increased prevalence of heart disease women their menopausal years, with clinical manifestations occurring predominantly older How much this increase risk phenomenon aging versus status remains controversial. Also, earlier onset and greater relative death bilateral oophorectomy or premature ovarian failure emphasizes importance estrogen determinant women.3o, 57 Of great concern are less favorable outcomes than men who defined events, both myocardial infarction revascularization procedures. Further, recent an array biologically plausible mechanisms benefit prevention been reviewed here. Finally, sizable number observational studies that suggest cardiovascular render compelling need evaluate precisely disease-gonadal relationships.