The value of EUS in predicting the response of gastric mucosa–associated lymphoid tissue lymphoma to Helicobacter pylori eradication

作者: Lara M.N. El-Zahabi , Faek R. Jamali , Ihab I. El-Hajj , Mohammed Naja , Ziad Salem

DOI: 10.1016/J.GIE.2006.05.009

关键词:

摘要: Background Gastric mucosa–associated lymphoid tissue (MALT) lymphoma is associated with Helicobacter pylori infection, and regression of the tumor has been described after its eradication. Objective To determine value EUS, in addition to other clinical/endoscopic features, predicting response low-grade MALT H Design A retrospective, single-center study. Setting Patients Twenty-two patients primary gastric were identified through a retrospective review charts seen at American University Beirut Medical Center. Only 19 histopathologically confirmed infection who had EUS staging included Main Outcome Measurements Regression as determined by follow-up endoscopy mucosal biopsies. Results disease restricted mucosa significantly higher rate complete remission eradication compared infiltrating into submucosa (77.8% vs 12.5%, P .007). There was no statistical difference terms mean time achieve such ( .212). Age, sex, location within stomach, endoscopic appearance did not correlate probability lymphoma. Limitations The limitations include design relatively small sample population. Conclusion determination invasion depth helps predict

参考文章(42)
C. Thiede, T. Wündisch, B. Neubauer, B. Alpen, A. Morgner, M. Ritter, G. Ehninger, M. Stolte, E. Bayerdörffer, A. Neubauer, Eradication of Helicobacter pylori and Stability of Remissions in Low-Grade Gastric B-Cell Lymphomas of the Mucosa-Associated Lymphoid Tissue: Results of an Ongoing Multicenter Trial Gastrointestinal Lymphoma. ,vol. 156, pp. 125- 133 ,(2000) , 10.1007/978-3-642-57054-4_16
Leticia Quintanilla-Martı́nez, Carmen Lome-Maldonado, German Ott, Andreas Gschwendtner, Evelyn Gredler, Edgardo Reyes, Arturo Angeles-Angeles, Falko Fend, Primary Non-Hodgkin's Lymphoma of the Intestine: High Prevalence of Epstein-Barr Virus in Mexican Lymphomas as Compared With European Cases Blood. ,vol. 89, pp. 644- 651 ,(1997) , 10.1182/BLOOD.V89.2.644
Gary M. Gray, Saul A. Rosenberg, Allen D. Cooper, Peter B. Gregory, David T. Stein, Howard Herzenberg, Lymphomas involving the gastrointestinal tract Gastroenterology. ,vol. 82, pp. 143- 152 ,(1982) , 10.1016/0016-5085(82)90138-X
Sergiu B. Cogliatti, Ulrico Schmid, Urs Schumacher, Friedjof Eckert, Martin-Leo Hansmann, Jürgen Hedderich, Hiroshi Takahashi, Karl Lennert, Primary B-cell gastric lymphoma: A clinicopathological study of 145 patients Gastroenterology. ,vol. 101, pp. 1159- 1170 ,(1991) , 10.1016/0016-5085(91)90063-Q
Donna M. Weber, Meletios A. Dimopoulos, Darshan P. Anandu, William C. Pugh, Gideon Steinbach, Regression of gastric lymphoma of mucosa-associated lymphoid tissue with antibiotic therapy for Helicobacter pylori Gastroenterology. ,vol. 107, pp. 1835- 1838 ,(1994) , 10.1016/0016-5085(94)90828-1
Bouzourene, Haefliger, Delacretaz, Saraga, The role of Helicobacter pylori in primary gastric MALT lymphoma Histopathology. ,vol. 34, pp. 118- 123 ,(1999) , 10.1046/J.1365-2559.1999.00597.X
A C Pavlick, H Gerdes, C S Portlock, Endoscopic ultrasound in the evaluation of gastric small lymphocytic mucosa-associated lymphoid tumors. Journal of Clinical Oncology. ,vol. 15, pp. 1761- 1766 ,(1997) , 10.1200/JCO.1997.15.5.1761
Graziella Pinotti, Emanuele Zucca, Enrico Roggero, Anna Pascarella, Francesco Bertoni, Antonella Savio, Emilici Savio, Carlo Capella, Ennio Pedrinis, Piercarlo Saletti, Emanuela Morandi, Giuseppe Santandrea, Franco Cavalli, Clinical features, treatment and outcome in a series of 93 patients with low-grade gastric MALT lymphoma. Leukemia & Lymphoma. ,vol. 26, pp. 527- 537 ,(1997) , 10.3109/10428199709050889
Shinji Ohashi, Kose Segawa, Shozo Okamura, Humihiro Urano, Shinichi Kanamori, Hideki Ishikawa, Kazuo Hara, Akira Hukutomi, Kennosuke Shirai, Matsuyoshi Maeda, A clinicopathologic study of gastric mucosa-associated lymphoid tissue lymphoma. Cancer. ,vol. 88, pp. 2210- 2219 ,(2000) , 10.1002/(SICI)1097-0142(20000515)88:10<2210::AID-CNCR3>3.0.CO;2-I