An update on the role of long non-coding RNAs in the pathogenesis of breast cancer.
作者： Bashdar Mahmud Hussen , Mohammad Taheri , Soudeh Ghafouri-Fard , Kasra Honarmand Tamizkar
DOI: 10.1016/J.PRP.2021.153373
关键词:
摘要: Breast cancer is the most frequent female malignancy. This malignancy has diverse clinical and molecular subtypes with different prognoses. Dysregulation of long non-coding RNAs (lncRNAs) not only participates in development breast cancer, but also affects course prognosis this type cancer. Hundreds studies have shown up-regulation or down-regulation lncRNAs samples serum affected individuals suggesting these RNA molecules as diagnostic markers for Different anticancer agents such trastuzumab, lapatinib, doxorubicin, hydroxyurea, docetaxel, 5-fluorouracil 6-thioguanine affect expression profile lncRNAs. In present article, we review results investigations about role evolution
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