New helper cells and matched early region 1-deleted adenovirus vectors prevent generation of replication-competent adenoviruses.
作者： Frits J. Fallaux , Abraham Bout , Ietje van der Velde , Diana J. M. van den Wollenberg , Kathleen M. Hehir
DOI: 10.1089/HUM.1998.9.13-1909
关键词:
摘要: The presence of replication-competent adenoviruses (RCAs) in batches of replication-defective adenovirus (Ad) vectors is a major problem for the application of these vectors in gene …
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