Globin Composition and Synthesis of Hemoglobins in Developing Fetal Mice Erythroid Cells

作者: A. Fantoni , A. Bank , P. A. Marks

DOI: 10.1126/SCIENCE.157.3794.1327

关键词:

摘要: Fetal mouse erythropoiesis proceeds initially in yolk-sac blood islands (8 to 12 days) and, subsequently, liver (12 at least 16 days). Yolksac cells synthesize three hemoglobins, Hb E(I), E(II) and E(III). E(I) has x- y-globin chains; alpha y; HB E(III), z. No detectable beta-globin is formed these cells. Liver erythroid form only adult hemoglobin, composed of alpha- beta-chains.

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