Antimicrobial resistance screening and profiles: a glimpse from the South African perspective.

摘要: According to the Centre for Disease Dynamics Economics and Policy, South Africa represents a paradox of antibiotic management similar other developing countries, with both overuse underuse (resulting from lack access) antibiotics. In addition, wastewater reuse may contribute towards resistance through selective pressure that increases in native bacteria on clinically relevant bacteria, increasing profiles common pathogens. Sediments surface water bodies sludge provide place where genes are transferred bacteria. Crop irrigation is thought be potential source exposure antibiotic-resistant transfer or into crops. The objectives this study were examine antibiotic-resistance Escherishia coli three agricultural locations Western Cape, Africa. Using classical microbiology culture approach, E. species isolated river sediments, farm dams their sediments passive algal treatment ponds sediment used crop assessed 13 commonly Randomly selected isolates tested resistance. 100% resistant sulphamethoxazole, highlighting its relevance African context. dam samples, only found fluoroquinolone fluorifenicol. ponds, differed those effluent, 90% effluent being ampicillin. Isolates less (40%) ampicillin, whereas all pond samples sulphamethoxazole. These results illustrate importance better understanding agriculture scenarios ensure remedial measures take greatest benefit can realised especially countries limited financial infrastructural resources. Moreover, as an effective, feasible alternative highlighted, comparable reducing overall samples.