Epidermal growth factor receptor gene copy number in 101 advanced colorectal cancer patients treated with chemotherapy plus cetuximab

作者: Carla Campanella , Marcella Mottolese , Anna Cianciulli , Angela Torsello , Roberta Merola

DOI: 10.1186/1479-5876-8-36

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摘要: Background Responsiveness to Cetuximab alone can be mediated by an increase of Epidermal Growth factor Receptor (EGFR) Gene Copy Number (GCN). Aim this study was assess the role EGFR-GCN in advanced colorectal cancer (CRC) patients receiving chemotherapy plus Cetuximab.

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