Increased lactate production follows loss of mitochondrial membrane potential during apoptosis of human leukaemia cells
作者： Martin Tiefenthaler , Albert Amberger , Nicole Bacher , Bernd L. Hartmann , Raimund Margreiter
DOI: 10.1046/J.1365-2141.2001.02988.X
关键词:
摘要: … Prior to the onset of apoptosis, ie prior to the loss of membrane potential, lactate production was reduced. … In control cells, in which apoptosis was not induced, we found no significant …
blackwell-synergy.com参考文章(29)
Imtiaz A Malik, Saleem Abubakar, Feroz Alam, Ata Khan, None, Dexamethasone-induced tumor lysis syndrome in high-grade non-Hodgkin's lymphoma. Southern Medical Journal. ,vol. 87, pp. 409- 411 ,(1994) , 10.1097/00007611-199403000-00024
Jinfang Li, Alan Eastman, Apoptosis in an Interleukin-2-dependent Cytotoxic T Lymphocyte Cell Line Is Associated with Intracellular Acidification ROLE OF THE Na/H-ANTIPORT Journal of Biological Chemistry. ,vol. 270, pp. 3203- 3211 ,(1995) , 10.1074/JBC.270.7.3203
Jason E. Reynolds, Alan Eastman, Michael A. Barry, Etoposide-induced Apoptosis in Human HL-60 Cells Is Associated with Intracellular Acidification Cancer Research. ,vol. 53, pp. 2349- 2357 ,(1993)
Stephan Geley, Reinhard Kofler, Monika Hála, Elisabeth M. C. Strasser-Wozak, Rosa Hattmannstorfer, Bernd L. Hartmann, Michael Fiegl, Splice Site Mutation in the Glucocorticoid Receptor Gene Causes Resistance to Glucocorticoid-induced Apoptosis in a Human Acute Leukemic Cell Line Cancer Research. ,vol. 55, pp. 348- 353 ,(1995)
E. Brad Thompson, Michael R. Norman, Characterization of a Glucocorticoid-sensitive Human Lymphoid Cell Line Cancer Research. ,vol. 37, pp. 3785- 3791 ,(1977)
Shigeomi Shimizu, Masashi Narita, Yoshihide Tsujimoto, Yoshihide Tsujimoto, Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC Nature. ,vol. 399, pp. 483- 487 ,(1999) , 10.1038/20959
H. M. Piper, T. Noll, B. Siegmund, Mitochondrial function in the oxygen depleted and reoxygenated myocardial cell Cardiovascular Research. ,vol. 28, pp. 1- 15 ,(1994) , 10.1093/CVR/28.1.1
I. Nicoletti, G. Migliorati, M.C. Pagliacci, F. Grignani, C. Riccardi, A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry Journal of Immunological Methods. ,vol. 139, pp. 271- 279 ,(1991) , 10.1016/0022-1759(91)90198-O
Klearchos K Papas, Lei Sun, Eric S Roos, John S Gounarides, Michael Shapiro, Carlo M Nalin, Change in lactate production in Myc-transformed cells precedes apoptosis and can be inhibited by Bcl-2 overexpression. FEBS Letters. ,vol. 446, pp. 338- 342 ,(1999) , 10.1016/S0014-5793(99)00240-9
G Basanez, A Nechushtan, O Drozhinin, A Chanturiya, E Choe, S Tutt, KA Wood, Y-T Hsu, J Zimmerberg, RJ Youle, None, Bax, but not Bcl-xL, decreases the lifetime of planar phospholipid bilayer membranes at subnanomolar concentrations Proceedings of the National Academy of Sciences of the United States of America. ,vol. 96, pp. 5492- 5497 ,(1999) , 10.1073/PNAS.96.10.5492