Induction of cervical dilation for transcervical embryo transfer in ewes.

作者: Ivanka BR Candappa , Pawel M Bartlewski

DOI: 10.1186/1477-7827-12-8

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摘要: Background A major limitation in the application of assisted reproductive technologies sheep arises from inability to easily traverse uterine cervix. The cervix non-pregnant ewe is a narrow and rigid structure, with 5–7 spiral folds crypts that block its lumen. first two closest vagina appear be greatest obstacle for instrument insertion into Therefore, dilation distal part could provide conformational change necessary perform non-invasive transcervical procedures. present study set out assess efficacy Cervidil®, patented dinoprostone (PgE2)-containing vaginal insert controlled-release mechanism, safely induce sufficient cervical purpose embryo transfer (TCET) cyclic ewes.

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