HER Family of Receptors as Treatment Targets in Pancreatic Cancer

Y Yarden, The EGFR family and its ligands in human cancer. signalling mechanisms and therapeutic opportunities. European Journal of Cancer. ,vol. 37, pp. 3- 8 ,(2001) , 10.1016/S0959-8049(01)00230-1

Beckmann S, Thybusch-Bernhardt A, Juhl H, Comparative analysis of the EGF-receptor family in pancreatic cancer: expression of HER-4 correlates with a favourable tumor stage. International journal of surgical investigation. ,vol. 2, pp. 393- 400 ,(2001)

Buchler M, Korc M, Kobrin Ms, Yamanaka Y, Friess H, Beger Hg, Coexpression of epidermal growth factor receptor and ligands in human pancreatic cancer is associated with enhanced tumor aggressiveness. Anticancer Research. ,vol. 13, pp. 565- 569 ,(1993)

E. Peles, R.B. Levy, E. Or, A. Ullrich, Y. Yarden, Oncogenic forms of the neu/HER2 tyrosine kinase are permanently coupled to phospholipase C gamma. The EMBO Journal. ,vol. 10, pp. 2077- 2086 ,(1991) , 10.1002/J.1460-2075.1991.TB07739.X

Sinkovics Jg, Oncogenes and growth factors Critical Reviews in Immunology. ,vol. 8, pp. 217- 298 ,(1988)

Adhip P.N. Majumdar, Jianhua Du, James S. Hatfield, Edi Levi, Volkan Adsay, Eva M. Schmelz, Kiran K. Nagothu, Richard Jaszewski, Omer Kucuk, Fazlul H. Sarkar, Expression of EGF-receptor related protein (ERRP) decreases in gastric mucosa during aging and carcinogenesis. Digestive Diseases and Sciences. ,vol. 48, pp. 856- 864 ,(2003) , 10.1023/A:1023078924686

S.A. Prigent, W.J. Gullick, Identification of c-erbB-3 binding sites for phosphatidylinositol 3'-kinase and SHC using an EGF receptor/c-erbB-3 chimera. The EMBO Journal. ,vol. 13, pp. 2831- 2841 ,(1994) , 10.1002/J.1460-2075.1994.TB06577.X

N S Pellegata, B Renault, F Sessa, E Solcia, G N Ranzani, M Bonato, B E Leone, K-ras and p53 Gene Mutations in Pancreatic Cancer: Ductal and Nonductal Tumors Progress through Different Genetic Lesions Cancer Research. ,vol. 54, pp. 1556- 1560 ,(1994)

E Livneh, R Prywes, O Kashles, N Reiss, I Sasson, Y Mory, A Ullrich, J Schlessinger, Reconstitution of human epidermal growth factor receptors and its deletion mutants in cultured hamster cells. Journal of Biological Chemistry. ,vol. 261, pp. 12490- 12497 ,(1986) , 10.1016/S0021-9258(18)67114-5

Didier Wion, Philippe Brachet, Neelakanta Ravindranath, Daniel Djakiew, Epidermal Growth Factor Modulates the Expression of Vascular Endothelial Growth Factor in the Human Prostate Journal of Andrology. ,vol. 22, pp. 432- 443 ,(2001) , 10.1002/J.1939-4640.2001.TB02199.X