Stroke in community-acquired bacterial meningitis: a Danish population-based study.

摘要: Summary Objectives Stroke is a serious complication in community-acquired bacterial meningitis (CABM), but the incidence, predispositions, and outcome need further clarification; this pertains particular to impact of pre-existing atherosclerosis risk factors. Therefore, we aimed assess these features retrospective population-based cohort study. Methods We included all patients over 16 years age with CABM North Denmark Region, 1998–2010. All data were retrieved from patient records. A Glasgow Outcome Scale score 1–4 was defined as an unfavourable 5 favourable. Results identified 152 episodes CABM. In 22 (14%) episodes, had stroke; 15 strokes ischaemic, three haemorrhagic, four combination both. Age factors not significantly associated stroke. However, stroke higher in-hospital mortality (27% vs. 16%; adjusted ratio (age aj. RR) 1.43, 95% confidence interval (CI) 0.67–3.04), (86% 37%; adj. RR 2.09, CI 1.59–2.75), long-term sequelae among survivors (88% 40%, 2.01, 1.53–2.65) compared without Conclusions common adult possibly also death. seemed be related