Green approaches to late-stage fluorination: radiosyntheses of 18F-labelled radiopharmaceuticals in ethanol and water
作者： Megan N. Stewart , Brian G. Hockley , Peter J. H. Scott
DOI: 10.1039/C5CC05919D
关键词:
摘要: Green strategies for late-stage fluorination with 18F, in which ethanol and water are the only solvents used throughout entire radiolabeling process (azeotropic drying, nucleophilic fluorination, purification formulation), have been developed applied to radiosyntheses of a range radiopharmaceuticals commonly employed clinical PET imaging.
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