Evaluation of the pituitary-adrenal axis in simple hirsutism.

作者: JOSEPH W. GOLDZIEHER , HOWARD LAITIN

DOI: 10.1210/JCEM-20-7-967

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摘要: ABSTRACT Pituitary-adrenal relationships were studied in 63 women with simple hirsutism, by means of urinary 17-ketosteroid and corticoid determinations under control conditions during maximal stimulation ACTH minimal suppression prednisolone. The data analyzed various statistical techniques including a matrix correlations. Involvement the adrenal cortex this clinical disorder was confirmed several functional parameters. It appears that adrenals hirsute patients may be more sensitive to fluctuations endogenous than are normal subjects, such hypersensitivity is largely confined ketosteroid-producing mechanism. Several features approach function tests, as well utility correlation discussed.

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