Cullin3–KLHL25 ubiquitin ligase targets ACLY for degradation to inhibit lipid synthesis and tumor progression
作者： Cen Zhang , Juan Liu , Grace Huang , Yuhan Zhao , Xuetian Yue
关键词:
摘要: … CUL3 interacts with ACLY through its adaptor protein, KLHL25 (Kelch-like family member 25), to ubiquitinate and degrade ACLY in cells. Through negative regulation of ACLY, CUL3 …
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