Assembling large genomes with single-molecule sequencing and locality-sensitive hashing

作者: Konstantin Berlin , Sergey Koren , Chen-Shan Chin , James P Drake , Jane M Landolin

DOI: 10.1038/NBT.3238

关键词:

摘要: Long-read, single-molecule real-time (SMRT) sequencing is routinely used to finish microbial genomes, but available assembly methods have not scaled well to larger genomes. We …

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