Biosensor based on antifouling PEG/Gold nanoparticles composite for sensitive detection of aflatoxin M1 in milk

摘要: Abstract Detection of ultra-trace amounts aflatoxin M1 (AFM1) is an important requirement for food safety since it a toxic mycotoxin, present in cow milk, with strictly regulated low levels. To achieve detection levels AFM1, we developed new nanometric aptasensing platform based on the modified SPCE, which was decorated AuNPs, tetraethylene glycol ferrocene derivative and anti-AFM1 aptamer. The tethered to AuNPs served as capacitance transducer contributing interfacial charge. capacitive signal used quantify toxin. This study revealed good sensitivity toward toxin dynamic range 20 300 pg·mL−1 LOD 7.14 pg·mL−1 (S/N = 3). nanoaptosensor exhibits very metrological performances. evaluate sensing platform, latter applied detect presence AFM1 pasteurized milk.